Psychedelics are a subset of hallucinogenic drugs whose primary effect is to trigger non-ordinary states of consciousness (known as psychedelic experiences or "trips" ) via serotonin 2A receptor agonism. This causes specific psychological, visual and auditory changes, and often a substantially altered state of consciousness. The "Classical" psychedelics, the psychedelics with the largest scientific and cultural influence, are mescaline, LSD, psilocybin, and DMT.

Most psychedelic drugs fall into one of the three families of chemical compounds: tryptamines, phenethylamines, or lysergamides. These chemicals all bind to serotonin 5-HT2A receptors,[2] which modulate the activity of key circuits in the brain involved with sensory perception and cognition, however the exact nature of how psychedelics induce changes in perception and cognition via the 5-HT2A receptor is still unknown, although reduced default mode network activity is likely a primary mechanism of action.[3][4] The psychedelic experience is often compared to non-ordinary forms of consciousness such as those experienced in meditation,[5][6] mystical experiences,[7][8] and near-death experiences.[8] The phenomenon of ego dissolution is often described as a key feature of the psychedelic experience.

Many psychedelic drugs are illegal worldwide under the UN conventions, with occasional exceptions for religious use or research contexts. Despite these controls, recreational use of psychedelics is common. Legal barriers have made the scientific study of psychedelics more difficult. Research has been conducted, however, and studies show that psychedelics are physiologically safe and do not lead to addiction.[11][12] Studies conducted using psilocybin in a psychotherapeutic setting reveal that psychedelic drugs may assist with treating depression and alcohol addiction, and possibly also nicotine addiction.[13][14] Although further research is needed, existing results are showing that psychedelics may be useful for treating certain forms of psychopathology
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Psychedelics are a group drugs whose main effect is to induce a mood changing effect on its consumer.
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