Overview of Vascular Graft Market

According to the latest report published by Transparency Market Research (TMR), the global vascular graft market is projected to expand at a considerable growth rate during the forecast period, owing to advancements in new technologies for novel product development and increase in demand for vascular surgeries.

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Vascular surgery is performed primarily around a blocked or narrowed artery to restore blood flow to an organ (such as the heart or brain) or an extremity (most commonly a leg). A surgeon connects a healthy artery to the narrowed artery beyond the blocked point with a natural or synthetic graft to create an alternative path for blood flow. Different types of vascular bypass graft surgeries are available depending on the location of the blockage; however, they are major procedures that require a lengthy recovery period. Thus, doctors and clinicians are signing consent forms from patients & educating them about the benefits & possible risks associated with vascular grafts devices to improve patient outcomes.

Coronary artery bypass grafting (CABG) is a major surgical procedure wherein atheromatous blockages in a patient's coronary arteries are bypassed with venous or arterial conduits harvested from the patient. The bypass restores blood flow to the ischemic myocardium, restoring function and viability, while also alleviating anginal symptoms.

Every year, nearly 400,000 CABG surgeries are performed, making it the most common major surgical procedure. However, an increase in the usage of alternative options such as medical treatment and percutaneous coronary intervention (PCI) has decreased the requirement for surgical treatments. Hence, companies are diversifying the usage of coronary artery bypass graft with variations in CABG surgeries such as minimally invasive CABG, robot-assisted CABG, and other hybrid procedures to prevent potential complications after the surgery.

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Rise in Prevalence Rate of Cardiovascular Diseases to Drive Global Vascular Graft Market

The rise in the number of patients suffering from cardiovascular diseases such as coronary artery disease and cardiac arrest is expected to drive the global vascular graft market. In the Americas, cardiovascular diseases (CVD), particularly ischemic heart disease and cerebrovascular disease (stroke), are the leading causes of death & a major contributor to disability in individuals. CVD is a significant contributor to the cost of medical care, as it is one of the leading causes of morbidity and mortality in patients. CVD accounted for nearly a third of all deaths globally in 2016.

On the other hand, CVD caused over 17 million deaths, which amounts to 330 million years of life lost, and 35.6 million years of disability worldwide in 2017. Meanwhile, CVD is likely to be the cause of more than 23 million deaths globally by 2030.

The demand for non-invasive/minimally invasive surgeries is increasing due to advantages such as faster recovery, less discomfort, shorter hospital stay, decrease in post-surgery complications, and less blood loss. This is expected to increase the number of vascular surgeries performed during the forecast period, whilst boosting the demand for vascular stents.

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Use of Endovascular Stent Grafts in Minimally Invasive Treatment to Improve Patient Outcome

In terms of product type, the endovascular stent graft segment held a significant market share in 2021. Endovascular grafting is a minimally invasive treatment option for aortic aneurysms. Instead of an open aneurysm repair, the surgeon may consider an endovascular aneurysm repair (EVAR). Such findings are propelling the demand for innovative stent grafts.

An endovascular stent graft is a tube made of fabric that is supported by a metal mesh known as a stent. It can be used to treat various blood vessel conditions, but it is most commonly used to reinforce a weak spot in an artery known as an aneurysm.

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Design Improvements in Synthetic Vascular Grafts Contributing to Market Growth

Based on source, the global vascular graft market has been categorized into synthetic, biological, and biosynthetic materials. The synthetic segment held a major share of 64% of the global market in 2021. This segment is anticipated to expand at a CAGR of more than 5.7% during the forecast period. This can be attributed to applications where synthetic vascular grafts are being used to patch injured or diseased areas of arteries or for the replacement of whole segments of large arteries such as the aorta.

In a reconstructive surgery, synthetic vascular grafts derived from expanded polytetrafluoroethylene (ePTFE) and Dacron have shown promising results for medium- or large-diameter vessel transplants. Vascular grafts made of synthetic materials can be created using cutting-edge tissue engineering techniques such as tissue engineering by self-assembly (TESA), electrospinning, and bioprinting. These innovations are paving way for design improvements in tissue‐engineered vascular grafts.

Synthetic materials have been used in vascular graft designs for various reasons. One of the most important reasons is the ease and flexibility with which their mechanical properties can be tailored. Most medical-grade polyurethanes are composed of soft domains made from polyester, polyether, or polycarbonate. In order to improve synthetic graft function and yield biohybrid conduits, various components are being added to the synthetic vascular graft designs.

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