On the defensive side in NBA 2K22 MT the back, the computer's defense and supplementary defense actions are faster and more violent as well as the effectiveness of powerful jumps and pick-and roll cuts are greatly diminished. Players might need to use more complicated strategies to be able to complete their offense quicker.

The most significant change in the next generation version is the "City of Basketball" in the MC mode. The "City of Basketball" in NBA 2K22 was reintroduced to the community mode in 2K18 19. It combines the main storyline with the huge "Basketball City" players must increase their market share through activities like fashion and music in addition to their basketball career. Develop into an NBA player with a full development of intelligence, morality physicality, artistic and labor.

The game follows the same plot as Buy 2K22 MT the 2K series. The AI, Junior, DJ and other characters played by players in the previous generations are now NPCs in the game. While the plot is well-developed and intricate, the script's interpretation of it isn't always consistent. Many of the important plots also lack logic. This is embarrassing for the profession model that is based on substitution.