Targeted DNA/RNA Sequencing: Introduction

• Targeted sequencing is a rapid and cost-effective method to detect known and novel variants in selected sets of genes or genomic regions. Gene sequencing can be accomplished using several different DNA sequencing methods, depending on the scale.
• Targeted RNA-sequencing (RNA-Seq) is a highly accurate method for selecting and sequencing specific transcripts of interest. It offers both quantitative and qualitative information. Targeted RNA-Seq can be achieved via either enrichment or amplicon-based approaches, both of which enable gene expression analysis in a focused set of genes of interest.

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Key Drivers of Global Targeted DNA/RNA Sequencing Market

• The global targeted DNA/RNA sequencing market is driven by continuous technological advancements and increase in availability of innovative & cost-effective sequencing platforms. Rise in usage of next generation sequencing methods such as exome sequencing and exome sequencing in research & development is projected to boost the growth of the global targeted DNA/RNA sequencing market during the forecast period.
• Major players focus on launch of new targeted DNA/RNA sequencing products. This is another major factor fueling the growth of the global market. For instance, in August 2020, Roche Molecular Systems, Inc. launched the new Exome and Custom KAPA Target Enrichment portfolio for translational and clinical applications in sequencing. In 2018, Twist Bioscience launched exome and custom target enrichment solutions for genomics and clinical researchers conducting next-generation sequencing.

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DNA-based Targeted Sequencing to be Highly Promising Segment

• In terms of type, the global targeted DNA/RNA sequencing market can be bifurcated into DNA-based targeted sequencing and RNA-based targeted sequencing. DNA-based targeted sequencing is expected to be the leading segment during the forecast period.
• DNA-based targeted sequencing is the most common method used for sequencing, as it is cost-effective, requires less time compared to other methods, and availability of a range of products to facilitate DNA-seq

Drug Discovery Segment to Dominate Global Market

• Based on application, the global targeted DNA/RNA sequencing market can be categorized into drug discovery, human biomedical research, plant & animal sciences, and others. The drug discovery segment is likely to dominate the global market during the forecast period.
• EXOME sequencing, exome sequencing, and others are the most commonly used and preferred methods for drug discovery

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Academic & Research Institutes to be Most Promising Segment

• In terms of end-user, the global targeted DNA/RNA sequencing market can be divided into hospitals & clinics, academic & research institutes, and pharma & biotech companies. The academic & research institutes segment held significant share of the market in 2020. The segment is projected to witness strong growth during the forecast period.
• Increase in research & development activities in the past few years has led to rise in demand for targeted DNA/RNA sequencing in academic & research institutes. Moreover, scholarships offered for NGS-based PhD projects are anticipated to propel the segment.

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North America to Dominate Global Targeted DNA/RNA Sequencing Market

• In terms of region, the global targeted DNA/RNA sequencing market can be segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa
• North America is projected to dominate the global market during the forecast period. However, the region is anticipated to lose market share by the end of 2027. Presence of large number of genome centers with installed sequencers and presence of major players drive the targeted DNA/RNA sequencing market in North America. Effective regulatory bodies to review the sequencing-based genetic tests and new technological advancements augment the market in the region.
• The targeted DNA/RNA sequencing market in Asia Pacific is expected to expand at a high CAGR during the forecast period

Key Players Operating in Global Targeted DNA/RNA Sequencing Market

The global targeted DNA/RNA sequencing market was highly fragmented in 2020.

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