Systemic Mastocytosis Treatment: Introduction
• Systemic mastocytosis is a rare disease in which mast cells accumulate in internal tissues and organs such as the liver, spleen, bone marrow, and small intestines. Systemic mastocytosis is majorly found in adult patients. Signs and symptoms vary according to the body parts that get affected. Generally, this disorder is caused due to somatic changes in KIT gene.
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• There are four types of systemic mastocytosis: indolent systemic mastocytosis (ISM), systemic mastocytosis with an associated hematologic nonmast cell lineage disorder (SM-AHNMD), aggressive systemic mastocytosis (ASM), and mast cell leukemia (MCL)
Key Drivers of Global Systemic Mastocytosis Treatment Market
• Non-profit organizations and government associations are majorly focusing on increasing awareness about systemic mastocytosis disorders, which is likely to drive the market during the forecast period. Furthermore, increase in research & development expenses from major pharmaceutical companies to develop new treatment options for systemic mastocytosis disorders further boosts the market.
• Major market players are focusing on the launch of new products in untapped regions, partnerships, collaborations, and acquisitions, which are projected to propel the systemic mastocytosis treatment market during the forecast period. In April 2017, Novartis received U.S. FDA Approval for Rydapt in the treatment of aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematological neoplasm (SM-AHN) and mast cell leukemia.
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Mast Cell Stabilizers Segment to be Highly Promising
• Based on drug type, the global systemic mastocytosis treatment market can be segmented into antihistamines, tyrosine kinase inhibitors, proton pump inhibitors, epinephrine, steroids, and mast cell stabilizers
• The mast cell stabilizers segment accounted for a prominent share of the global systemic mastocytosis treatment market in 2019. This segment is expected to dominate the systemic mastocytosis treatment market, as it exhibits high efficiency in the treatment of systemic mastocytosis.
Indolent Systemic Mastocytosis (ISM) Segment to be Highly Promising
• Based on indication, the global systemic mastocytosis market can be classified into indolent systemic mastocytosis (ISM), systemic mastocytosis with an associated hematologic nonmast cell lineage disorder (SM-AHNMD), aggressive systemic mastocytosis (ASM), and mast cell leukemia (MCL)
• The indolent systemic mastocytosis (ISM) segment accounted for a prominent share of the global systemic mastocytosis market in 2019. The segment is expected to dominate the systemic mastocytosis market due to an increase in number of patients suffering from indolent systemic mastocytosis (ISM).
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Injectable Segment to Expand Significantly
• In terms of route of administration, the global systemic mastocytosis market can be divided into oral, injectable, and topical. Injectable was a prominent segment, in terms of revenue, in 2019. It is anticipated to expand significantly during the forecast period.
• Most of products are available in the injectable form and rapid onset of action are likely to drive the segment
Retail Pharmacies to be Most Promising Segment
• In terms of distribution channel, the global systemic mastocytosis treatment market can be divided into hospital pharmacies, retail pharmacies, and online pharmacies. Retail pharmacies was a prominent segment of the market, in terms of revenue, in 2019. It is anticipated to expand significantly during the forecast period.
• Most systemic mastocytosis treatment is easily available in retail pharmacy stores and high footfall of patients are estimated to fuel the retail pharmacy segment during the forecast period
North America to Dominate Global Systemic Mastocytosis Treatment Market
• In terms of region, the global systemic mastocytosis treatment market can be categorized into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa
• North America dominated the global systemic mastocytosis treatment market in 2019. It is expected to maintain its leading position during the forecast period. Dominance of the region can be attributed to an increase in number of patients with systemic mastocytosis and increasing awareness about diseases and new product launches.
• The market in Asia Pacific is projected to expand at a significantly high growth rate during the forecast period, owing to an increase in prevalence of systemic mastocytosis in emerging countries such as India and China
Key Manufacturers Operating in Global Market
The global systemic mastocytosis treatment market was highly fragmented in 2019. Key manufacturers operating in the global market are:
• Bausch Health Companies Inc.
• Pfizer Inc.
• Merck & Co. Inc.
• Mylan NV
• Teva Pharmaceutical Industries Ltd.
• Sanofi S.A.
• Johnson & Johnson
• Novartis AG
• Bayer AG
• Mallinckrodt Pharmaceuticals
• EPI Health, LLC
• Kaleo Inc
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