Pramlintide Acetate

Molecular Formula:C171H267N51O53S2
CAS No.:196078-30-5
Product Description:Pramlintide powder
Appearance :White powder
Water Content(Karl Fischer) :≤5.0%
Acetate Content(by HPLC) :≤12.0%
Amino Acid Composition :±10% of theoretical
Purity (by HPLC) :≥98.0%
Single Impurity(by HPLC) :≤1.0%
Peptide Content(by %N ) :≥80%
Assay(By Anhydrous, Acetic Acid-free ) :95.0~105.0%
Bacterial Endotoxins :≤5EU/mg
Pharmacology:
Synthetic analog of the naturally occurring neuroendocrine hormone amylin.
Amylin is colocated with insulin in pancreatic beta cells and is cosecreted with insulin in response to food intake. Amylin slows gastric emptying, suppresses glucagon secretion, and regulates food intake by centrally mediated modulation of appetite.