In the 2010 NBA draft, Paul George was chosen by the Indiana pacers in the first round of the first round. Paul George scored 13 points, seven rebounds and five steals in his 95-86 victory over the Washington wizards at the pacers, breaking his career record. The NBA released its rookie lineup for the 2010-11 season, and Paul George was named the second-best rookie of the year.

Paul George played for the pacers in 61 regular-season games, starting 19 of them with 7.8 points and 3.7 rebounds per game. In the 2011 postseason NBA MT Coins, Paul George was the only player outside Landry fields to be named in the starting lineup for 2010. In the pedestrians on the road 98-87 victory over the Dallas mavericks, Paul George had 30 points, nine rebounds and five assists and five steals, made 7, 11 of his three-point attempts to refresh in a career game, three hit record.