Perricone recommends an anti-inflammatory diet that includes consuming a high quality protein (such as tuna or salmon), adequate amounts of essential fatty acids, as well as colorful fresh fruits and vegetables. The reason this diet works to reduce inflammation is because it supplies a number of essential nutrients that can heal inflammatory conditions such as arthritis and autoimmune disease.Essential fatty acids Smart Blood Sugar like those found in salmon, flax, nuts, seeds and olive oil, can significantly curb inflammation, reduce pain and swelling, improve joint mobility and prevent further degeneration of joints. However they have to be taken over months to see a noticeable effect.Supplementation with folic acid has been found to reduce hip fractures resulting from osteoporosis.

Taking a good supplement that provides bone minerals such as magnesium and calcium is essential for sufferers of joint pain. Zinc has also been shown to relieve joint pain and stiffness. A good supplement will also include Vitamin D and B6, as well as antioxidant vitamins like A, C and E.Other nutritional substances that have been shown to significantly reduce inflammation in a number of studies are turmeric, which was found to reduce symptoms by 73%, and bromelain, a protease enzyme derived from pineapples. Anti-oxidants like alpha-lipoic acid are also recommended as part of the anti-inflammatory diet.MSM (methylsulfonylmethane), an organic sulfur-containing nutrient, has proved helpful in relieving symptoms of knee osteoarthritis and reducing pain.

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