Market Analysis and Insights: Global Hemophagocytic Lymphohistiocytosis Treatment Market
hemophagocytic lymphohistiocytosis treatment market is expected to grow at a substantial CAGR in the forecast period of 2019-2026. Special designation from the regulatory authority can and high unmet need of disease is fueling the market growth.
Hemophagocytic lymphohistiocytosis is rare disorder of the immune system in which both histocytes and lymphocytes start to proliferate and attacks body tissues and organs. It can be inherited conditions or it can be results of immunosuppression and infection.
According to the statistics published in the Centers for Disease Control and Prevention an estimated annual incidence of just one cases in every 50,000 live birth for familial hemophagocytic lymphohistiocytosis. Growing cases of immune-oncology disorders worldwide and increased access to novel treatment options for these conditions are factors that drive the market growth.
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Competitive Analysis:
Global hemophagocytic lymphohistiocytosis treatment market is highly fragmented and the major players have used various strategies such as new product launches, expansions, agreements, joint ventures, partnerships, acquisitions, and others to increase their footprints in this market. The report includes market shares of global hemophagocytic lymphohistiocytosis treatment market for Global, Europe, North America, Asia-Pacific, South America and Middle East & Africa.
Market Drivers
• Increase prevalence of oncology and immunology disorders worldwide as these can increase the risk of hemophagocytic lymphohistiocytosis is enhancing the market growth
• Huge financial support to the researchers for developing novel intervention is boosting the market growth
• High demand of disease specific novel treatment can also act as a market driver
• Increase in strategic alliances between the companies to expedite the development faster is propelling the growth of the market
Market Restraints
• Hemophagocytic lymphohistiocytosis is challenging to diagnose since the initial symptoms mimic common infections acting as a challenging factor for the growth of this market
• Low healthcare budget in some developing countries is hamper the market growth
• Stringent and hefty regulation is also acting as restrains for the growth of this market
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Segmentation: Global Hemophagocytic Lymphohistiocytosis Treatment Market
By Type
• Familial
• Acquired
By Therapy Type
• Immunotherapy
• Chemotherapy
• Targeted Therapy
• Others
By Treatment
• Medication
• Surgery
By Drugs
• Emapalumab
• Alemtuzumab
• Infliximab
• Others
By Route of Administration
• Oral
• Parenteral
By End Users
• Hospitals
• Homecare
• Specialty Clinics
• Oncologist
• Immunologist
• Others
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Key Developments in the Market:
• In November 2018, SOBI received approval from the FDA for Gamifant (emapalumab-lzsg), an interferon gamma-blocking monoclonal antibody for the treatment of refractory, recurrent, or progressive primary hemophagocytic lymphohistiocytosis for adult and pediatric (newborn and older) patients. This drug received an Orphan Drug designation, Priority Review, Breakthrough Therapy designation and Rare Pediatric Disease Designation from the FDA. The approval of Gamifant represents major advances in the treatment of these underserved patient populations through a targeted mode of action.
• In November 2016, AB2 Bio Ltd received an Orphan Drug Designation from the European Medicines Agency for Tadekinig alfa (IL-18BP) for the treatment of haemophagocytic lymphohistiocytosis.With this designation, company can obtain regulatory and financial incentives for development and marketing along with market exclusivity.
Key Market Players:
Few of the major competitors currently working in the global hemophagocytic lymphohistiocytosis treatment market are SOBI, AB2 Bio Ltd, Alpine Immune Sciences, Bellicum Pharmaceuticals, Inc, Sanofi, Pfizer Inc, Johnson & Johnson Services, Inc, Samsung Bioepis, Incyte Corporation and others.
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