Depending on the location of treatment, drug detoxification differs, but the majority of detox centres offer treatment to prevent the physical withdrawal symptoms from alcohol and other drugs. Some methods of alternative medicine assert that through herbal, electrical, or electromagnetic treatments, the body can be cleansed of "toxins" (such as the Aqua Detox treatment).

Drug detoxification is used to lessen or eliminate withdrawal symptoms while assisting the addicted person in adjusting to life without drugs; it is not intended to treat addiction but rather to serve as the first phase of long-term therapy. Drug-free detoxification is possible, but it's also possible to utilise pharmaceuticals as part of the process. In a community programme that lasts several months and takes place in a residential facility rather than a medical facility, drug detoxification and treatment frequently take place.

Alcohol detoxification is typically handled by the liver and kidneys in the body. Alternative alcohol detoxification methods are however required in cases of alcohol addiction treatment in order to reverse the harm and causes that alcohol has. Many physicians, nurses, and pharmacists work as volunteers in alcohol detoxification facilities for alcoholics.

Through oxidation, conjugation, and excretion of molecules from cells or tissues, an animal's metabolism can result in poisonous compounds that are then rendered less toxic. Diet detoxification: Some diets operate under the premise that the body builds up toxins that need to be eliminated, particularly during periods of binge eating or the intake of processed and non-nutritious foods.

As with alternative medicine, there is no scientific support for the claim that the 'toxins' eliminated are undefined and are attributed to foods, the environment, and the body's own wastes. Most detox diets advise drinking more water—at least eight glasses each day. Detoxification is the term used to describe alcohol detox treatment because of the aforementioned factors.

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