Cell therapy, also known as cellular therapy or cytotherapy, is a type of biotherapy used to develop therapeutic strategies and drugs based on living cells. Cell therapy refers to biological activities exerted by cellular material that would cause a preferred effect either in vitro or in vivo. Over the years, an increasing number and range of cell types suitable for exogenous administration have been identified, with healing activity proven in animal models for various disorders. In cell therapy, cell suspensions are inserted into the blood stream or into a tissue or organ with the potential that the injected cells would heal any injury that has happened or that is enduring.
Research on cell therapy is ongoing; however, numerous cell types have been developed into treatments as innovative cell therapies and considered for impending medical applications. Hematopoietic stem cell transplantation is the most commonly used cell therapy for the treatment of various blood cancers and hematologic conditions. Probable uses of cell therapies include treatment of autoimmune disease, cancers, infectious disease & urinary problems, rejuvenating injured cartilage in joints, fixing spinal cord injuries, improving weakened immune system, and improving patients with neurological disorders.
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Presently, governments of developed as well as developing countries are engaged in research & development and commercialization of cell therapy products. Directing the cell therapy product into high potential and enough effective value market. This would be the beginning of new age technology to recognize, understand, and establish personalized medicine, thereby driving the cell therapy products market. However, unclear guidelines for the manufacture of cell therapy products, no specified clinical research procedure for establishing the efficacy of treatment, and side effects are factors hampering the growth of the market.
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Cell therapy signifies a new standard of medicine and is precisely very significant and also very meaningful as the world’s growth engine in post-IT era. These products have applications in a large number of disorders. These include diseases of the nervous system and cancer. Other applications are cardiac disorders such as heart failure and myocardial infarction, diabetes mellitus, ailments of bones and joints, genetic disorders, and injuries of the skin and soft tissues.
The global cell therapy products market can be segmented based on technology, type of cell, source of cell, application, and end-user. In terms of type of cell, the market can be bifurcated into autologous and allogeneic. Based on technology, the global cell therapy products market can be classified into cell immortalization, somatic cell technology, genome editing technology, viral vector technology, three-dimensional technology, and cell plasticity technology. The viral vector technology segment can be categorized into ex vivo and in vivo gene modifications. In terms of source of cell, the market can be divided into bone marrow, induced pluripotent stem cells (iPSCs), adipose tissue, umbilical cord blood-derived cells, and neural stem cell. Based on application, the global cell therapy products market can be classified into gastrointestinal, musculoskeletal, neurological, wound care, cardiovascular, oncology, dermatology, and others. In terms of end-user, the market can be categorized into hospitals & specialty clinics, diagnostic centers, research institutes, regenerative medicine centers, and others.
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In terms of region, the global cell therapy products market can be segmented into North America, Latin America, Europe, Asia Pacific, and Middle East & Africa. North America accounted for the dominant share of the global market in 2018 owing to high research and development activities and increase in adoption of cell therapy products in the region. In North America, development of new cell therapies is supported by significant funding by governments and other regulatory bodies. Asia Pacific is one of the fastest developing economies in the world. Government initiatives is the major factor propelling the market in the region. The Government of South Korea invested US$ 100 Bn in research and development in 2012. The Ministry of Health and Welfare launched Global Stem Cell and Regenerative Medicine Initiative and invested KRW 45 Bn in R&D (US$ 15 Bn) in 2011. The Ministry of Education and Science Technology invested KRW 40 Bn in 2011 and KRW 49 Bn in 2012 and supports transitional clinical research in the field of stem cell and regenerative medicine. Moreover, rise in awareness about cell therapy and its benefits augment the cell therapy products market in Asia Pacific.
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Major players operating in the global cell therapy products market include NuVasive, Inc., PHARMICELL Co., Ltd., Stemedica Cell Technologies, Inc., Fibrocell Science, Inc., Anterogen. Co., Ltd., Osiris Therapeutics, Inc., JCR Pharmaceuticals Co. Ltd., Cellectis, Pluristem, and Advanced Tissue.
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