Biktarvy is a combination medicine of bictegravir (BIC), emtricitabine (FTC), and tenofovir alafenamide. BIC inhibits the strand transfer activity of HIV-1 integrase (integrase strand transfer inhibitor; INSTI), an HIV-1 encoded enzyme required for viral replication. FTC, a synthetic nucleoside analog of cytidine, is phosphorylated by cellular enzymes to form emtricitabine 5'-triphosphate. TAF is a phosphoramidate prodrug of tenofovir (2′-deoxyadenosine monophosphate analog). This medicine is used for treating human immunodeficiency virus type 1 (HIV-1) infection. This medicine is supplied in 50 mg/200 mg /25 mg.
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