Autologous chondrocyte implantation is a surgical technique used to repair damages in the articular cartilage. This implantation is carried out in two separate surgical technique. The major surgical method is an arthroscopic technique, during which a detailed evaluation of the joint is prepared and a cartilage bioscopy is conducted. The cells extracted in the biopsy are enzymatically treated to isolate the chondrocyte, which is the cartilage constructing cells of the body. The isolated cells are re-implanted into the damaged area within the joint in second technique. Autologous chondrocyte implantation allows patients suffering from articular cartilage damage to regain mobility. The overall success rate of autologous chondrocyte implantation surgery is nearly 85%.
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Based on procedure type, the global autologous chondrocyte implantation market can be segmented into gel-type autologous chondrocyte implantation (GACI), matrix-type autologous chondrocyte implantation (MACI), and collagen-type autologous chondrocyte implantation (CACI). The gel-type autologous chondrocyte implantation segment is likely to expand at a significant pace during the forecast period as compared to the other segments, because many surgeon prefer the use of GACI process in repair of cartilage damage of the knee, as it is easy, quick and very effective for restoring patient knee function and also connection with the normal tissue is very smooth. In terms of materials used, the autologous chondrocyte implantation market can be segmented into collagen membrane, hyaluronan polymer, polylactin copolymer and polyglactin copolymer. The collagen membrane segment is expected to expand at a significant pace due to its wide availability. The collagen membrane acts as a strong barriers to prevent epithelial migration. It has quick regenerative features that heal the affected area. Increasing number of road accidents and industrial accidents and growing prevalence of osteoarthritis worldwide are primary factors driving the autologous chondrocyte implantation market. Additionally, growing sports activities has increased the number of injury. This has led to high incidence of various fracture-related problems. Moreover, according to the Truven Health Marketscan Database, more than 2.4 million procedures are performed annually around the globe to address ligament, cartilage, or tendon injuries in the knee. However, inadequate health care facilities, longer recovery process, poor or lack of reimbursement in developing countries are restraining the market in these countries.
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In terms of region, the global autologous chondrocyte implantation market can be segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. North America dominates the global market. This region is projected to hold a significant share of the global market, due increase in orthopedic procedures and adoption of technologically advanced products. Moreover, growing prevalence of osteoarthritis in the U.S.is a major cause of disability. In 2012, osteoarthritis effected 20.0 million people and expected to reach 40.0 million over the next 10 year. Increasing adoption of different technique in knee surgeries for advanced health care and rising awareness regarding the treatment of knee injuries are boosting the market in Europe. Expansion of the health care sector and rise in geriatric population coupled with increasing demand for minimally invasive surgeries are key factors boosting the adoption of autologous chondrocyte implantation. Additionally, untapped developing economies such as China and India are projected to further propel the autologous chondrocyte implantation market. Advancements in surgeries, increasing per capita income and growing incidence of osteoarthritis are likely to augment the market for autologous chondrocyte implantation in Middle East & Africa during the forecast period.
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Major players operating in the global autologous chondrocyte implantation market are B.Braun Melsungen AG, Zimmer Biomet Holding Inc., Smith & Nephew plc, Osiris Therapeutics, Inc., Stryker Corporation, and Vertical Corporation.
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