Aging is a natural process concerning physiological, cellular, psychological, social changes of an organism over a period. It is not just restricted to a single region rather affecting the whole world. By 2050, the world's population aged 60 years and older is expected to reach 2 billion, up from 900 million in 2015. Currently, 125 million people are aged 80 years or above. Countries like India where the population pyramid was of expanding type will soon show a change due to the aging and increased life expectancy. It leads to the onset of several eye defects. Some of the eye defects are hereditary such as aniridia. It is a congenital, hereditary, bilateral, extreme form of iris hypoplasia that may be associated with other ocular defects. It describes an extreme form of iris hypoplasia in which the iris appears absent on superficial clinical examination. However, gonioscopy shows the presence of the iris root. Aniridia is not just an isolated defect in iris development but is a panocular disorder with macular and optic nerve hypoplasia, cataract, and corneal changes that are other anomalies that lead to decreased vision and nystagmus. Other conditions that lead to the disruption of iris include Iris hypoplasia, Congenital mydriasis and Iris coloboma. advent of artificial iris lead to the therapeutic treatment of this condition. Artificial iris derived a revenue of US$ 10.61 Million in 2018 and is expected to fetch US$ 16.28 Million by 2025 displaying tremendous CAGR of 6.39% over the forecast period (2019-2025).

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The global artificial iris market is segmented based on material type (Fiber and Fiber Free), Age group (Pediatric and Adult Cohorts), colour (blue, brown and other colour), application (cosmetic and therapeutic) and end-users (hospitals, eye surgery centers and other end user) are the major focus areas considered while analyzing and defining the penetration of artificial iris at global scale. Under the material type segment, in 2018, the fibre-free dominated the global artificial iris market with the maximum share in terms of revenue. Based on estimation, the segment occupied 55.3% share in 2018. Adult Cohorts dominated the age group segment. Amongst the colour segment blue colour dominated the market with a revenue of US$ 4.75 million in 2018, followed by brown. Therapeutics is the application of the artificial iris and is utilized by the patients suffering from major iris defects. Hospital is the major institution where patients undergo this procedure of artificial iris implantation.

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Also, for better understanding of the overall adoption rate of artificial iris in different market, detailed analysis has been done for different regions/countries including North America (US, Rest of the North America), Europe (Germany, Netherlands and Rest of the Europe), Asia Pacific (China, India, Japan and Rest of the APAC), and the rest of the world (Middle East and Latin America). Based on the estimation, Europe dominated the global artificial iris market, accounting for revenue share of 41.2% in 2018. On account of the strong presence of major market players.

Numerous companies have earmarked their presence in the global artificial iris market with continued focus on product expansions, investments, business expansion, product launches and collaborations. Some of the major players operating in the global artificial iris market include Ophtec, HumanOptics AG, Morcher, ReperNN, VEO Ophthalmics, Spectrum Surgical, Eye-yon Medical and Pixium vision.

Global artificial iris market generated revenue of US$ 10.61 million in 2018. The technology is expected to grow at a CAGR of 6.39% during the forecast period to reach a market valuation of US$ 16.28 million by 2025. Europe dominated the global artificial iris, accounting for revenue share of 41.2% in 2018.

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TABLE OF CONTENTS:

1. MARKET INTRODUCTION

1.1 Market Definition 16

1.2 Objective of the Study 16

1.3 Limitation 16

1.4 Stakeholders 16

1.5 Currency used in the Report 17

1.6 Scope of the Global Artificial Iris Market Study 17

2. RESEARCH METHODOLOGY OR ASSUMPTION 18

2.1 Research Methodology for Global Artificial Iris Market Study 18

2.1.1 Main objective of the Artificial Iris Market Study 19

3. INDUSTRY PERFORMANCE 20

4. EXECUTIVE SUMMARY 22

5. CURRENT AND PROJECTED SCENARIO OF THE WORLD'S EYESIGHT 24

5.1 General Overview 24

5.1.1 Key Facts on the state of the world's eyesight 24

5.1.2 Improving the world’s Eyesight; the Goals of Vision 2020 28

6. MARKET OVERVIEW 30

6.1 Introduction 30

6.2 Market Dynamics 31

6.2.1 Market Drivers 31

6.2.1.1 Accelerating Geriatric Population 31

6.2.1.1.1 Some of the Key Facts regarding Ageing and health 31

6.2.1.2 Growing Number of Eye Defects 33

6.2.1.3 Increasing Demand of Minimally Invasive Surgical Procedures 34

6.2.1.4 Rising Healthcare Expenditure and Health-Conscious Personals 34

6.2.2 Market Restraints 38

6.2.2.1 Side Effects Associated with Implant Procedure 38

6.2.2.2 Lack of Reimbursement 38

6.2.2.3 Lack of Trained Professionals 39

6.2.3 Market Opportunities 39

6.2.3.1 Artificial Intelligence (AI) in Ophthalmology 39

7. TECHNIQUES FOR ARTIFICIAL IRIS IMPLANTATION 41

7.1 Overview 41

7.1.1 Surgical Techniques 41

7.1.2 Techniques 42

7.1.3 Sector- or Segment-Shaped Artificial Iris Sutured Side-by-Side to the Residual Iris 43

7.1.4 Injector-Assisted Sulcus-Fixated Complete Iris in Pseudophakic Eyes 43

7.1.5 Injector-Assisted Implantation of a Complete Iris in the Capsular Bag in Combination with Planned Standard Cataract Surgery 43

7.1.6 Complete Iris Prosthesis Implantation Sutured to the Sclera in Combination with a Scleral-Fixated Intraocular Lens in Aniridia and Aphakia of Vitrectomized Eyes 44

7.1.7 “Sandwich” or “Backpack” Iris Prosthesis Implantation in Combination with an Intraocular Lens in Aniridia and Aphakia 44

7.1.8 Open-Sky Implantation During a Perforating Keratoplasty 45

8. DEMAND AND SUPPLY SIDE ANALYSIS 46

8.1 Demand Side Analysis 46

8.2 Supply Side Analysis 47

8.2.1 Top Product Launch 48

8.2.2 Top Partnerships 48

8.2.3 Top Business Expansion & Investment 48

8.2.4 Value Chain Analysis of Artificial Iris 49

9. PIPELINE ACTIVITY 50

9.1 EndoArt Artificial Endothelial Layer: Eye-yon Medical 50

9.1.1 Product Description 50

9.1.2 Research and Development 50

9.2 Retinal Implant System (IRIS): Intelligent Medical Implants 51

9.2.1 Product Description 51

9.2.2 Research and Development 51

10. MARKET INSIGHTS BY MATERIAL TYPE 52

10.1 General Overview 52

10.1.1 Fiber Artificial Iris 54

10.1.1.1 Case Study: Comparison of complication rate for artificial iris with or without mesh 55

10.1.2 Fiber-free Artificial Iris 56

11. MARKET INSIGHTS BY COLOUR 58

11.1 General Overview 58

11.1.1 Blue Colour Artificial Iris 60

11.1.2 Brown Colour Artificial Iris 61

11.1.3 Other Colour Artificial Iris 61

12. MARKET INSIGHTS BY APPLICATION 63

12.1 General Overview 63

12.1.1 Cosmetic Application 64

12.1.2 Therapeutic Application 65

13. MARKET INSIGHTS BY AGE GROUP 67

13.1 General Overview 67

13.1.1 Pediatric 68

13.1.2 Adults 71

14. MARKET INSIGHTS BY END-USERS 73

14.1 General Overview 73

14.1.1 Hospitals 74

14.1.2 Eye Surgery Centers 75

14.1.3 Others Eye Care Facility 77

15. MARKET INSIGHTS BY REGION 78

15.1 General Overview 78

15.2 North America Artificial Iris Market (2018-2025) 80

15.2.1 North America Artificial Iris Market by Material Type 80

15.2.2 North America Artificial Iris Market by Colour 81

15.2.3 North America Artificial Iris Market by Application 81

15.2.4 North America Artificial Iris Market by Age Group 82

15.2.5 North America Artificial Iris Market by End-User 82

15.2.6 North America Artificial Iris Market by Country 83

15.2.6.1 United States Artificial Iris Market (2018-2025) 83

15.2.6.1.1 Eye Health Statistics, US 84

15.2.6.1.2 US Health Spending by Type of Service or Product, 2017 85

15.2.6.1.3 Health Spending by Major Sources of Funds 87

15.2.6.1.4 US Artificial Iris Market by Material Type 88

15.2.6.1.5 US Artificial Iris Market by Colour 88

15.2.6.1.6 US Artificial Iris Market by Application 89

15.2.6.1.7 US Artificial Iris Market by Age Group 89

15.2.6.1.8 US Artificial Iris Market by End-User 90

….continued

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NORAH TRENT

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