Indian Pharma's Blog (106)

Bendamustine: Medicine for Non-Hodgkin’s lymphoma

The drug Bendamustine is used to treat patients who have chronic lymphocytic leukemia and non-Hodgkin’s lymphoma. The multiple-doses vials of Bendamustine come in 100 mg for intravenous administration. The injection is supplied as sterile, clear, and colorless to a yellow ready-to-dilute solution. The active ingredient in the medicine is Bendamustine hydrochloride, and the inactive ingredients are propylene glycol, monothioglycerol, in polyethylene glycol. …

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Added by Indian Pharma on July 5, 2022 at 2:09am — No Comments

Carfilzomib: Single-use vial in 60 mg

The drug Carfilzomib is a sterile, white to off-white lyophilized powder, and it is a modified tripeptidyl epoxide isolated as the crystalline-free base. Carfilzomib is a tetrapeptide epoxyketone proteasome inhibitor that irreversibly binds to the N-terminal threonine-containing active sites of the 20S proteasome, the proteolytic core particle within the 26S proteasome. This drug is used in the treatment of multiple myeloma and the patient who has received at least a couple of prior therapies,… Continue

Added by Indian Pharma on June 28, 2022 at 4:47am — No Comments

Cytarabine: A nucleoside metabolic inhibitor

The drug Cytarabine is a nucleoside metabolic inhibitor, which healthcare professionals use for treating patients with acute non-lymphocytic leukemia of adults and pediatric patients. The medicine comes in 100 mg, 500 mg, and 1000 mg single-use vials for intravenous administration. This drug comes as an odorless, white to off-white crystalline powder. The active ingredient in the medicine is Cytarabine, and the inactive ingredients are sodium chloride and Water for Injection.…

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Added by Indian Pharma on June 23, 2022 at 1:22am — No Comments

Afinitor Tablets: An Antineoplastic Chemotherapy Medicine

Afinitor is formulated in the form of tablets and aimed to treat certain sorts of kidney or breast cancer, or brain tumor and certain types of advanced/progressive tumors of the stomach, intestines, or pancreas. The afinitor tablets are also aimed to treat certain sorts of seizures or benign tumors of the brain or kidney in individuals with a genetic condition named tuberous sclerosis complex. It is a cancer… Continue

Added by Indian Pharma on June 20, 2022 at 6:53am — No Comments

Denosumab: A human IgG2 monoclonal antibody

Denosumab, a human IgG2 monoclonal antibody and it binds to RANKL, a transmembrane or soluble protein essential for the formation, function, and survival of osteoclasts, the cells responsible for bone resorption. Increased osteoclast activity, stimulated by RANKL, is a mediator of bone pathology in solid tumors with osseous metastases. Denosumab helps in treating patients with increased bone mass in males at a higher risk for the fracture, receiving androgen deprivation therapy for the… Continue

Added by Indian Pharma on June 15, 2022 at 8:56am — No Comments

Carfilzomib: An intravenous infusion

The healthcare providers use the drug Carfilzomib for treating patients suffering from multiple myeloma who have received at least a couple of prior therapies, including bortezomib and an immunomodulatory agent. This drug is available in 60 mg single-use vials to administer intravenously. Carfilzomib is an antineoplastic drug that comes as a sterile, white to off-white lyophilized powder. The active ingredient in the medicine is Carfilzomib, and the inactive ingredients are sulfobutylether… Continue

Added by Indian Pharma on June 13, 2022 at 4:42am — No Comments

Bendamustine: An alkylating drug

Bendamustine is an alkylating drug; it is a bifunctional mechlorethamine derivative containing a purine-like benzimidazole ring. This medicine comes in single-use vials for intravenous infusion in 100 mg. The active ingredient in the drug is Bendamustine hydrochloride, and the inactive ingredient is mannitol. One should take this medicine as per the prescription of the doctor. Bendamustine is used in treating chronic lymphocytic leukemia and non-Hodgkin’s lymphoma.…

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Added by Indian Pharma on June 6, 2022 at 1:24am — No Comments

Lenalidomide: All you need to know about the medication

The drug Lenalidomide is a thalidomide analogue, is an immunomodulatory agent with antiangiogenic and antineoplastic properties. Lenalidomide is present as an off-white to pale-yellow solid powder, and the capsules of Lenalidomide come in the strengths of 5 mg, 10 mg, 15 mg, and 25 mg for oral administration. The active ingredient in the capsule is Lenalidomide, and the inactive ingredients are lactose anhydrous, microcrystalline cellulose, croscarmellose sodium, and magnesium stearate.…

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Added by Indian Pharma on June 1, 2022 at 6:40am — No Comments

Carfilzomib: A tetrapeptide epoxyketone proteasome inhibitor

The drug Carfilzomib is sold under the trade name Kyprolis. It is used in treating patients with multiple myeloma and has received at least a couple of prior therapies, including bortezomib and an immunomodulatory agent. Carfilzomib is a tetrapeptide epoxyketone proteasome inhibitor that irreversibly binds to the N-terminal threonine-containing active sites of the 20S proteasome, the proteolytic core particle within the 26S proteasome. It is an antineoplastic agent available for intravenous…

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Added by Indian Pharma on May 30, 2022 at 1:23am — No Comments

Bortezomib: Mantle cell lymphoma medicine

Healthcare professionals use the drug Bortezomib in treating patients who have multiple myeloma and mantle cell lymphoma. Bortezomib is a reversible inhibitor of the chymotrypsin-like activity of the 26S proteasome in cells of mammals. The 26S proteasome is a large protein complex that degrades ubiquitinated proteins. The drug Bortezomib single-vial comes in 2 mg for subcutaneous and intravenous infusion. The active ingredient in the vials is Bortezomib, with the inactive ingredient…

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Added by Indian Pharma on May 25, 2022 at 2:23am — No Comments

Bendamustine 50 MG: A Unique Alkylating Agent For CLL and NHL

Bendamustine 50 mg is a unique alkylating agent, which combines a nitrogen mustard moiety of mechlorethamine with a benzimidazole. The bendamustine 50 mg injection has shown promising clinical activity against a range of hematologic malignancies and solid tumors as a single agent or along with certain other anticancer agents. This medicinal product is indicated for the treatment of patients with chronic…

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Added by Indian Pharma on May 20, 2022 at 2:29am — No Comments

Cytarabine: A sterile, preservative-free solution

Cytarabine is found in a sterile, preservative-free, purple, lyophilized cake in a single-dose vial. This medicine is used in treating patients with acute myeloid leukemia or AML with myelodysplasia-related changes. Cytarabine comes in 100 mg, 500 mg, and 1000 mg for intravenous administration. One should administer this medication according to the prescription of the healthcare professional.

Cytarabine injection…

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Added by Indian Pharma on May 18, 2022 at 1:59am — No Comments

Rituximab: A CD20-directed cytolytic antibody

Rituximab is a CD20-directed cytolytic antibody, which healthcare professionals use for treating patients with Non–Hodgkin’s Lymphoma (NHL), Chronic Lymphocytic Leukemia (CLL), rheumatoid arthritis, Granulomatosis with Polyangiitis, and Microscopic Polyangiitis (MPA) and moderate to severe pemphigus Vulgaris. The single-dose vials of Rituximab come in 500 mg/50 mL (10 mg/mL) to administer intravenously. Rituximab is produced in Chinese Hamster Ovary suspension culture in a nutrient medium…

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Added by Indian Pharma on May 12, 2022 at 2:22am — No Comments

Arsenic Trioxide: All you need to know about the medication

The medicine Arsenic Trioxide is a sterile, nonpyrogenic, clear solution. Healthcare professionals recommend this drug to treat patients who have acute promyelocytic leukaemia (APL) who are refractory to or have relapsed from retinoid and anthracycline chemotherapy and whose APL is characterized by the presence of the t(15;17) translocation or PML/RAR-alpha gene expression. Arsenic trioxide does morphological changes and DNA fragmentation characteristic of apoptosis in NB4 human…

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Added by Indian Pharma on May 6, 2022 at 6:09am — No Comments

Cytarabine Injection: A Type of Antimetabolite

Cytarabine injection helps stop cells from forming DNA and may kill malignant cells. It is a type of antimetabolite. Also known as ARA-C. The cytarabine injection price might vary depending on a wide range of generic and innovator version drugs. Cytarabine is a medication used with other medicines for the treatment of adults and children with acute myeloid leukemia (AML) and for the prevention and treatment of a…

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Added by Indian Pharma on May 4, 2022 at 2:03am — No Comments

A manual of Arsenic Trioxide drug

The medicine Arsenic Trioxide is recommended by healthcare professionals for treating patients with acute promyelocytic leukemia who are refractory to or have relapsed from retinoid and anthracycline chemotherapy and whose APL is characterized by the presence of the t(15;17) translocation or PML/RAR-alpha gene expression. The active ingredient in the medicine is Arsenic Trioxide, and the inactive ingredients are sodium hydroxide and hydrochloric acid.…

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Added by Indian Pharma on April 28, 2022 at 5:36am — No Comments

All you need to know about Bendamustine

Bendamustine is a bifunctional mechlorethamine derivative containing a purine-like benzimidazole ring. Mechlorethamine and its derivatives form electrophilic alkyl groups. Bendamustine is used by healthcare professionals in the treatment of patients with chronic lymphocytic leukemia and non-Hodgkin’s lymphoma. The active ingredient in the medicine is Bendamustine hydrochloride, and the inactive ingredients are propylene glycol, monothioglycerol, in polyethylene glycol. Bendamustine injection…

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Added by Indian Pharma on April 26, 2022 at 2:15am — No Comments

Carfilzomib 60 mg Injection: A Chemotherapy Medication

Carfilzomib 60 mg is approved as a chemotherapy agent to treat patients with multiple myeloma who have taken single or multiple lines of therapy. The carfilzomib 60 mg injection price in India is less than the other countries due to the availability of both biosimilar drugs and their brand-name counterparts. The proposed dosing regimen of Carfilzomib 60 mg can be administered once or twice weekly, and your…

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Added by Indian Pharma on April 21, 2022 at 2:45am — No Comments

Bendamustine: chronic lymphocytic leukemia treatment

Healthcare providers use Bendamustine in treating patients who have chronic lymphocytic leukemia and non-Hodgkin’s lymphoma. This drug comes in single-use vials in 100 mg to inject intravenously. The recommended dosage of Bendamustine is 100 mg/m2 administered intravenously over 10 minutes on Days 1 and 2 of a 28-day cycle, up to 6 cycles. Bendamustine is an alkylating agent.

Bendamustine injection 100…

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Added by Indian Pharma on April 18, 2022 at 1:53am — No Comments

Pomalidomide: Capsules to administer orally

Pomalidomide is an analog of thalidomide drug, which healthcare professionals use to treat patients with multiple myeloma. It is an immunomodulatory agent with antineoplastic activity. In trials, Pomalidomide inhibited proliferation and induced apoptosis of hematopoietic tumor cells. Moreover, Pomalidomide inhibited the proliferation of lenalidomide-resistant multiple myeloma cell lines and synergized with dexamethasone in both lenalidomide-sensitive and lenalidomide-resistant cell lines to…

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Added by Indian Pharma on April 12, 2022 at 2:02am — No Comments

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